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内容推荐 鉴于肿瘤免疫治疗(PD1/PD-L1,CAR-T)取得的巨大进展以及对人类健康的深远影响,本书将以全新的视角、国际化的视野,以该领域最新的研究成果为主体,围绕肿瘤免疫治疗的两个思路(一是靶标肿瘤细胞,二是活化免疫细胞),系统地阐述肿瘤免疫治疗的基本原理及临床应用,同时也对肿瘤免疫治疗提出新的期望。该书为英文版,教师可以通过本书介绍的最新研究成果,切实提高专业课程的教学水平。与此同时,基础医学和临床医学的研究生通过本书的学习,可以全面掌握肿瘤免疫治疗的核心思路,为他们以后从事相关科研工作提供新的视角。 目录 Chapter 1 Introduction 1.1 Basics of the Human Immune System 1.2 Conception of Tumor Immunotherapy 1.3 Progress of Tumor Immunotherapy 1.4 Clinical Progress in Tumor Immunotherapy Chapter 2 Biomarker of Tumor 2.1 Conception of Biomarker in Tumor 2.2 Role of Biomarker in Tumor 2.3 Biomarker of Tumor in Immunotherapy Chapter 3 Therapeutic Antibody 3.1 Target Immune Cells 3.2 Target Microenvironment in Tumor 3.3 Target Solid Tumor Chapter 4 Immune Checkpoint Inhibitor 4.1 PD-1/PD-L1 Signal Pathway 4.2 PD-1/PD-L1 Inhibitor 4.3 CTLA-4 Inhibitor 4.4 Other Monoclonal Antibody 4.5 Adverse Reactions and Management Chapter 5 Tumor Vaccine 5.1 Whole-Cell Vaccine 5.2 Polypeptide Vaccine 5.3 Gene Engineering Vaccine 5.4 Nuclei Acid Vaccine Chapter 6 Adaptive T Cell Transfer 6.1 Lymphokine-Activated Killer 6.2 Tumor Infiltrating Lymphocytes 6.3 Natural Killer Cell 6.4 Cytokine-Induced Killer 6.5 Cytotoxic T Lymphocyte 6.6 CAR-T 6.7 TCR-T Chapter 7 Immune System Modulators 7.1 Cytokine Therapy 7.2 Small Molecule Immune Modulators 7.3 Immune Adjuvant 7.4 Indoleamine 2,3-dioxygenase 7.5 Role of Indoleamine 2,3-dioxygenase Inhibitor |