蛇葡萄素（Ampelopsin）又名双氢杨梅素（dihydromyricetin，DMY）是藤茶中一种重要的黄酮类物质。研究表明，Ampelopsin具有广泛的生物学功能：抗炎、抗氧化、抗肿瘤、保肝、改善运动疲劳等。本书首从Ampelopsin的结构入手，然后分章节来探讨Ampelopsin的抗炎、抗氧化、抗肿瘤、保肝、神经保护、改善运动疲劳及衰老性肌萎缩的作用；阐明Ampelopsin发挥上述作用的信号分子或者靶标；Ampelopsin发展成为功能性食品的前景。

Chapter 1 Pharmacological potential of ampelopsin in Rattan tea
Chapter 2 Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-KB signaling pathways
Chapter 3 Natural products for cancer prevention associated with Nrf2-ARE pathway
Chapter 4 Anti-tumor effect
4.1 Potential molecular targets of ampelopsin in prevention and treatment of cancers
4.2 Nutraceutical or pharmacological potential of Moringa oleifera Lam
4.3 Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways:involvement of p38 and ERK
Chapter 5 Neuroprotective effect
5.1 Ampelopsin inhibits H2O2-induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase
5.2 Ampelopsin attenuates 6-OHDA-induced neurotoxieity by regulating GSK-3β/NRF2/ARE signaling
Chapter 6 Autophagy and brain aging
6.1 Autophagy as the modulator of neuronal homeostasis and neurodegenerative disorders
6.2 Resveratrol as a natural autophagy regulator for prevention and treatment of Alzheimer' s disease
6.3 Ampelopsin attenuates brain aging of D-gal-induced rats through miR-34a-mediated SIRT1/mTOR signaling pathway
6.4 Swimming attenuates D-galactose-induced brain aging via suppressing miR-34a-mediated autophagy impairment and abnormal mitochondrial dynamics
6.5 Voluntary wheel running exercise suppresses brain aging of rats through activating miR-130a-mediated autophagy
Chapter 7 Sarcopenia
7.1 Research progress of sarcopenia
7.2 MicroRNA-regulated proinflammatory cytokines in sarcopenia
7.3 Ampelopsin attenuates D-gal-induced oxidative stress-related skeletal muscle atrophy through activating AMPK/SIRT1/PGC-lα signaling cascade
7.4 Role and regulation of autophagy in mass maintenance of skeletal muscle
Acknowledgement
References