光散射现象在自然界中广泛存在，光散射分析化学是近年来的一个热点研究领域，已成为分析科学的重要分支。本书主要介绍了光散射分析技术的方法、原理及其在生物大分子、有机小分子和药物中的分析应用。

本书可作为从事分子光谱分析工作的研究生以及相关领域科研人员的参考书。

Chapter 1 Developing Process of Light Scattering Technique Analysis

1.1 Resonance Light Scattering Technique Used for Biochemical and Pharmaceutical Analysis

1.2 The Principles and Analytical Applications of Total Internal Reflected Resonance Light

 Scattering Technique

1.3 Recent Developments of the Resonance Light Scattering Technique: Technical Evolution,

 New Probes and Applications

Chapter 2 Analytical Applications in DNA Detection of Light Scattering Technique

2.1 Determination of Nucleic Acids by a Resonance Light-scattering Technique

 with α,β,γ,δ-tetrakis [4-(trimethylammoniumyl)phenyl]Porphine

2.2 Hybridization Detection of DNA by Measuring Organic Small Molecule Amplified Resonance

 Light Scattering Signals

2.3 Determination of Nanograms of Nucleic Acids by their Enhancement Effect on the Resonance

 Light Scattering of the Cobalt(II)/4-[(5-chloro -2-pyridyl) azo]- 1,3-diaminobenzene complex

2.4 Interactions of Janus Green B with Double Stranded DNA and the Determination of DNA

 Dased on the Measurement of Enhanced Resonance Light Scattering

2.5 A Sensitive and Selective Assay of Nucleic Acids by Measuring Enhanced Total Internal

 Reflected Resonance Light Scattering Signals Deriving from the Evanescent Field

 at the Water/Tetrachloromethane Interface

2.6 Backscattering Light Detection of Nucleic Acids with Tetraphenylporphyrin-Al(III)-Nucleic

 Acids at Liquid/Liquid Interface

2.7 Directly Light Scattering Imaging of the Aggregations of Biopolymer Bound Chromium(III)

 Hydrolytic Oligomers in Aqueous Phase and Liquid/Liquid Interface

Chapter 3 Analytical Applications in Protein Detection of Light Scattering Technique

3.1 Determination of Protein Concentration by Enhancement of the Preresonance Light-scattering

 of α,β,γ,δ-tetrakis(5-sulfothienyl) Porphine

3.2 On the Factors Affecting the Enhanced Resonance Light Scattering Signals of the Interactions

 Between Proteins and Multiply Negatively Charged Chromophores Using Water Blue as an Example

3.3 Determination of Proteins with α,β,γ,δ-tetrakis(4-sulfophenyl) Porphine by Measuring

 the Enhanced Resonance Light Scattering at the Air/Liquid Interface

3.4 A BackscatteringLight Detection Assembly for Sensitive Determination of Analyte

 Concentrated at the Liquid/Liquid Interface Using the Interaction of Quercetin with Proteins as

 the Model System

3.5 Flow-injection Resonance Light Scattering Detection of Proteins at the Nanogram Level

3.6 Resonance Light Scattering Imaging Detection of Proteins

 with α,β,γ,δ-tetrakis (p-sulfophenyl) Porphyrin

Chapter 4 Analytical Applications in Organic Micromolecles and Medicines Detection of

 Light Scattering Technique

4.i Enhanced Plasmon Resonance Light Scattering Signals of Colloidal Gold Resulted

 from its Interactions with Organic Small Molecules Using Captopril as an Example

4.2 Total Internal Reflected Resonance Light Scattering Determination of Chlortetracycline

 in Body Fluid with the Complex Cation of Chlortetracycline-europium-trioctyl Phosphine Oxide

 at the water/tetrachloromethane interface

4.3 Novel Assay of Thiamine Based on its Enhancement of Total Internal Reflected Resonance

 Light Scattering Signals of Sodium Dodecylbenzene Sulfonate at the Water/Tetrachloromethane

 Interface

4.4 Adsorption of PeniciUin-berberine Ion Associates at a Water/Tetrachloromethane Interface

 and Determination of Penicillin Based on Total Internal-reflected Resonance Light Scattering

 Measurements

4.5 Pharmacokinetic Detection of Penicillin Excreted in Urine Using a Totally Internally

 Reflected Resonance Light Scattering Technique with Cetyltrimethylammonium Bromide

4.6 A Wide Dynamic Range Detection of Biopolymer Medicines with Resonance Light Scattering

 and Absorption Ratiometry

4.7 A resonance Light Scattering Ratiometry Applied for Binding Study of Organic Small

 Molecules with Biopolymer

4.8 A Light Scattering and Fluorescence Emission Coupled Ratiometry Using the Interaction

 of Functional CdS Quantum Dots with Aminoglycoside Antibiotics as a Model System

4.9 Resonance Light Scattering Imaging Determination of Heparin

4.10 Visual Detection of Sudan Dyes Based on the Plasmon Resonance Light Scattering Signals

 of Silver Nanoparticles