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书名 | 生物化学 英文版 第2版 |
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作者 | 赵宝昌,关一夫 编 |
出版社 | 科学出版社 |
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简介 | 内容推荐 本书是我国高等医学院校留学生本科教学和中英双语教学班教学的生物化学教材,内容为医学专业学生应该掌握的基础理论、基本知识和基本技能,同时也兼顾了国家执业医师考试的要求。全书20章,内容包括蛋白质、核酸和酶的结构与功能;糖、脂、氨基酸和核苷酸的代谢,以及生物氧化和代谢整合与调节;DNA、RNA和蛋白质的生物合成,基因表达的调控和DNA技术;细胞信号转导,癌基因、抑癌基因和生长因子;肝胆、血液、维生素与无机物的生物化学;基因组学与其他组学。全书预计图350幅,表格约70个。本书特别注重在华留学生和双语教学的需要,重要英文生化专业名词与术语均在其后标出相应的中文,并在书后附有名词释义,给出简明、准确的概念。各章后附有中、英文小结。各章均设有知识框,介绍与临床的联系、研究方法、名人逸事等,以延伸学生的知识面,激发学生学习的积极性和创新精神。 目录 Introduction Chapter 1 Structures and Functions of Proteins 1.1 Amino Acid Composition in Proteins 1.2 Molecular Structure of Proteins 1.3 Structure-Function Relationship of Proteins 1.4 Classification of Proteins 1.5 Protein Physicochemical Properties and Protein Exploration Chapter 2 Structures and Functions of Nucleic Acids 2.1 Structural Units of Nucleic Acids--Nucleotides 2.2 Structures and Functions of DNA 2.3 Structures and Functions of RNA 2.4 Properties of Nucleic Acids 2.5 Nucleases Chapter 3 Vitamins 3.1 Fat-soluble Vitamins 3.2 Water-soluble Vitamins Chapter 4 Enzymes 4.1 Structure and Function of Enzymes 4.2 Properties and Catalytic Mechanisms of Enzymes 4.3 Kinetics of Enzyme-Catalyzed Reactions 4.4 Regulatory Enzymes 4.5 Nomenclature and Classification of Enzymes 4.6 Clinical Applications of Enzymes Chapter 5 Glycoconjugates 5.1 Molecular Structures of Glycans 5.2 Structures and Functions of Glycoproteins 5.3 Structures and Functions of Proteoglycans 5.4 Structures and Functions of Glycolipids Chapter 6 Biological Oxidation 6.1 Electron Transport Chain 6.2 Oxidative Phosphorylation 6.3 ATP and the Other High Energy Compounds 6.4 Selective Transport across the Inner Mitochondrial Membrane 6.5 Other Biological Oxidations Chapter 7 Carbohydrate Metabolism 7.1 Digestion and Absorption of Carbohydrates 7.2 Anaerobic Degradation of Glucose 7.3 Aerobic Oxidation of Glucose 7.4 Pentose Phosphate Pathway 7.5 Glycogen Formation and Degradation 7.6 Gluconeogenesis 7.7 Blood Sugar and Its Regulation Chapter 8 Lipid Metabolism 8.1 Fatty Acids and Derivatives of Polyunsaturated Fatty Acids 8.2 Digestion and Absorption of Lipids 8.3 Metabolism of Fats 8.4 Metabolism of Phospholipids 8.5 Metabolism of Cholesterol 8.6 Metabolism of Plasma Lipoproteins Chapter 9 Protein Catabolism 9.1 Nutritional Roles of Dietary Proteins 9.2 Digestion, Absorption and Putrefaction of Dietary Proteins 9.3 Degradation of Protein in Cells 9.4 General Catabolism of Amino Acids 9.5 Metabolism of Ammonia 9.6 Individual Amino Acid Catabolism Chapter 10 Nucleotide Metabolism 10.1 Biological and Medical Functions of Nucleotides 10.2 Degradation of Nucleic Acids 10.3 Metabolism of Purine Nucleotides 10.4 Metabolism of Pyrimidine Nucleotides 10.5 Deoxyribonucleotide Biosynthesis 10.6 Biosynthesis of Nucleoside Diphosphate and Nucleoside Triphosphate 10.7 Dysmetabolism of Nucleotides and Antimetabolites Chapter 11 Blood Biochemistry 11.1 Plasma Proteins 11.2 Structure and Function of Albumin 11.3 Synthesis of Hemoglobin and Its Regulation 11.4 Metabolism of Blood Cells Chapter 12 Liver Biochemistry 12.1 The Role of Liver in Material Metabolism 12.2 Hepatic Biotransformation 12.3 Metabolism of Bile Acid 12.4 Bile Pigment Metabolism and Jaundice Chapter 13 Mineral Biochemistry 13.1 Calcium, Phosphorus, and Magnesium Metabolism 13.2 Trace Elements Chapter 14 Integration and Regulation of Metabolism 14.1 Common Characteristics of Metabolism 14.2 Intereonnections of Metabolism 14.3 Metabolic Speizations of Some Organs 14.4 Regulatory Strategy of Metabolism Chapter 15 DNA Biosynthesis 15.1 General Features of DNA Replication 15.2 Enzymology and Topology of DNA Replication 15.3 Replication of Prokaryotic Systems 15.4 Replication of Eukaryotic Systems 15.5 Reverse Transcription and Other Modes of DNA Replication Chapter 16 DNA Damage and Repair 16.1 DNA Damage 16.2 Repair of DNA Damage 16.3 Significance of DNA Damage and Repair to DNA Damage Chapter 17 RNA Biosynthesis and Processing 17.1 Overview of Transcription 17.2 Transcription in Prokaryotes 17.3 Transcription in Eukaryotes 17.4 Processing of Eukaryotic RNAs Chapter 18 Protein Biosynthesis, Modification and Targeting 18.1 Machinery Involved in Translation 18.2 Amino Acid Activation 18.3 Protein Biosynthesis Journey 18.4 Protein Posttranslational Modifications and Targeting 18.5 Clinical Correlation of Protein Biosynthesis Chapter 19 Regulation of Gene Expression 19.1 General Characteristics of Gene Expression 19.2 Regulation of Gene Expression in Prokaryotes 19.3 Regulation of Gene Expression in Eukaryotes Chapter 20 DNA Technologies 20.1 Molecular Hybridization 20.2 DNA Sequencing 20.3 Polymerase Chain Reaction 20.4 Recombinant DNA Technology 20.5 Transgenesis and Gene Targeting 20.6 Gene Diagnosis and Gene Therapy Chapter 21 Signal Transduetion 21.1 Signal Molecules 21.2 Receptors 21.3 Signal Transduction Pathways 21.4 Signal Transduction Network 21.5 Signal Transduction and Medicine Chapter 22 Oncogenes, Tumor Suppressor Genes and Growth Factors 22.1 Oncogenes 22.2 Tumor Suppressor Genes 22.3 Growth Factors Chapter 23 Genomics, Proteomics, and Other Omics 23.1 Genomics 23.2 Proteomics 23.3 Other Omics 23.4 Omics and Medicine The Major References Index Glossary |
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