Chapter 1 Tools of the Cell Biologist
MICROSCOPY: ONE OF THE EARLIEST TOOLS
OF THE CELL BIOLOGIST
MORE TOOLS OF CELL BIOLOGY
SUMMARY
SUGGESTED READINGS
Chapter 2 Cell Membranes
THE MOLECULAR STRUCTURE OF CELL
MEMBRANE
MEMBRANE TRANSPORT OF SMALL
MOLECULES
SUMMARY
SUGGESTED READINGS
Chapter 3 Cytoskeleton
MICROFILAMENTS
INTERMEDIATE FILAMENTS
MICROTUBULES
SUMMARY
SUGGESTED READINGS
Chapter 4 Organelle Structure and Function
THE NUCLEUS
ENDOPLASMIC RETICULUM
THE GOLGI COMPLEX
ENDOCYTOSIS, ENDOSOMES, AND
LYSOSOMES
MITOCHONDRIA
PEROXISOMES
SUMMARY
SUGGESTED READINGS
Chapter 5 Cell Nucleus and Gene Expression
CELL NUCLEUS
DNA REPLICATION AND REPAIR ARE
CRITICAL NUCLEAR FUNCTIONS
GENE EXPRESSION
SUMMARY
SUGGESTED READINGS
Chapter 6 Cell Adhesion and the Extracellular
Matrix
CELL ADHESION
INTERCELLULAR JUNCTIONS
CELL ADHESION HAS MANY IMPORTANT
ROLES IN TISSUE FUNCTION
CELL ADHESION RECEPTORS TRANSMIT
SIGNALS THAT REGULATE CELL
BEHAVIOR
EXTRACELLULAR MATRIX
SUMMARY
SUGGESTED READINGS
Chapter 7 Intercellular Signaling
GENERAL MODES OF INTERCELLULAR
SIGNALING
HORMONES
GROWTH FACTORS
GASES: NITRIC OXIDE AND CARBON
MONOXIDE
NEUROTRANSMITTERS
SUMMARY
SUGGESTED READINGS
Chapter 8 Cell Signaling Events
SIGNALING IS OFTEN MEDIATED BY CELLSURFACE
RECEPTORS
RECEPTOR TYROSINE KINASES AND RASDEPENDENT
SIGNAL TRANSDUCTION
SIGNALING BY CATALYTIC RECEPTORS
SERINE-THREONINE KINASES
SIGNALING BY NONKINASE RECEPTORS
SIGNALING BY G-PROTEIN-COUPLED
RECEPTORS INVOLVES CLEAVAGE
OF GUANOSINE TRIPHOSPHATE TO
GUANOSINE DIPHOSPHATE
SIGNALING BY STEROID HORMONE
RECEPTORS REQUIRES LIGAND
INTERACTION WITHIN THE
CYTOPLASM OR NUCLEUS
OTHER SIGNALING PATHWAYS
SIGNALING BY THE RENINANGIOTENSIN
ALDOSTERONE SYSTEM
SIGNALING BY THE JAK/STAT PATHWAY
CALCIUM/CALMODULIN SIGNAL
TRANSDUCTION
SIGNALING BY ION CHANNEL RECEPTORS
SUMMARY
SUGGESTED READINGS
Chapter 9 The Cell Cycle and Cancer
CELL CYCLE: HISTORY
THE CELL CYCLE IS REGULATED BY
CYCLIN AND RELATED PROTEINS
MITOSIS
MEIOSIS
SENSORS RECOGNIZE SITES OF DNA
DAMAGE
CELL-CYCLE ALTERATIONS AND CANCER
SUMMARY
SUGGESTED READINGS
Chapter 10 Programmed Cell Death
DISTINCT FORMS OF PROGRAMMED CELL
DEATH
NEUROTROPHIN RECEPTORS
CASPASES
SIGNALING PATHWAYS THAT PROMOTE
CELL SURVIVAL
APOPTOSIS AND HUMAN DISEASE
SUMMARY
SUGGESTED READINGS

本书主要包括10部分，分别介绍了细胞生物学的基本概念、细胞膜及其表面、细胞质和细胞器、细胞核、细胞分裂繁殖与生长发育、细胞工程、细胞生物学的现状和前瞻等方面的内容。本教材可作为医学院校各专业本科学生的基础课教材，同时也是医学院校各专业研究生、教师及临床医师、药师获得这方面系统知识的一本有益读物。