由刘克良、程卯生和孟庆斌主编的《多肽化学与生物学(英文版)(精)》是一本英文版的药学化学专业著作,它阐述了包括创新的合成方法、结构和多肽和蛋白质的构象,和蛋白质材料科学、技术进步在肽纯化和分析、肽药物发现和设计、生物活性肽,配体受体相互作用,化学生物学界面和具有挑战性的问题在多肽。
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书名 | 多肽化学与生物学(英文版)(精) |
分类 | 科学技术-自然科学-生物科学 |
作者 | 刘克良//程卯生//孟庆斌 |
出版社 | 化学工业出版社 |
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简介 | 编辑推荐 由刘克良、程卯生和孟庆斌主编的《多肽化学与生物学(英文版)(精)》是一本英文版的药学化学专业著作,它阐述了包括创新的合成方法、结构和多肽和蛋白质的构象,和蛋白质材料科学、技术进步在肽纯化和分析、肽药物发现和设计、生物活性肽,配体受体相互作用,化学生物学界面和具有挑战性的问题在多肽。 目录 Preface The 12th Chinese International Peptide Symposium (CPS-2012) Acknowledgements Cathay Award Xiaoyu Hu Memorial Award Chinese Peptide Symposium Abbreviations Session 1 Innovative Methodology of Peptide/ Protein Synthesis N-to-C Sequential Ligation Method for Protein Total Synthesis Renliang Yang, Wen Hou, Xiaohong Zhang, Chuan-Fa Liu Total Solid-phase Combinatorial Synthesis of Biologically Active N-Decanoyl Depsipeptide Derivatives from Natural Products Chuanguang Qin, Qiuyu Wang, Lin Li, Tingting Wei, Jin Ren The Synthesis of Alkyne-human Relaxin-2 for Labeling with Different Azido Molecules by Click Chemistry Feng Lin, Linda Chan, Laszlo Otvos Jr.and John D.Wade 4-Methoxybenzyloxymethyl Group as a Thiol Protecting Group for Cysteine to Prevent Racemization in Fmoc Chemistry Hajime Hibino, Yuji Nishiuchi Bio-Inspired Thrombomodulin Conjugate Engineering via Recombinant and Bio-Orthogonal Conjugation Technique Hailong Zhang, Jacob Weingart, Rui Jiang and Xue-Long Sun Acid-catalyzed N-S Acyl Shift for Preparing Peptide Thioesters Using Fmoc Chemistry Yibo Qiu, Clarence T. T. Wong and James P. Tam Solid-Phase Synthesis of Side-Chain-Protected Peptides via a Linker- Modified Resin Zhi-Ping Huang, Ming Zhang Development of Peptide Modification Methods to Widely Expand Peptide Structural Diversity and Its Applications Xinjun Zhang, Wentao Zhang Session 2 Peptide/Protein Material Sciences Synthetic and Self-assembly Studies of a Series of Gemini Peptides Changhai Cao, Meiwen Cao, Daohong Xia, Hai Xu Fabrication of Globular Protein/Polysaccharide-PAA Aggregates Naipu He, Sikai Huang, Xi Du, Weigang Zhao, Shengfang Lu, Xiaoqian Han High-efficiency Cellular Penetrable Superparamagnetic Nanoparticle Complexation with Tat Peptide Conjugates Chenhong Wang, Lei Qiao, Keliang Liu Biological Activities of Integrin-binding Peptides Derived from Laminins on Alginate and Chitosan Matrices Kazuhiro Sato, Yuji Yamada, Kentaro Hozumi, and Motoyoshi Nomizu Session 3 Technological Advances in Peptide Purification and Analysis Intein-mediated Expression of Cyclic Sunflower Trypsin Inhibitor in E. coli Shunyi He, Ting Chen, Wei Zhang, Rong Feng, Youshang Zhang Perfection of the Universal Method for Screening Affinity Adsorbents Used for Phosphorylated Peptide Isolation Utilizing Gold Colloids Qinqin Wei, Wei Wang, Bicui Wang, Jun Wang, Zhi Yuan Session 4 Peptide drug discovery and design New Paradigms for Drug Discovery and Development: Design of Multivalent Ligands for the Treatment of Disease Victor J. Hruby, Takashi Yamamoto, Padma Nair, Minying Cai, Josef Vagner, Jatinder Josan, Robert J. Gillies, Liping Xu, David Morse, Peg Davis, Shou-Wu Ma, Tally Largent-Milnes, Josephine Lai, Eva Varga, Todd Vanderah, Frank Porreca Edible Biologics: Orally Active Peptide Bradykinin B1 Receptor Antagonists for Inflammatory Pain Treatment James P. Tam, Clarence T. T. Wong Small-sized BACE1 Inhibitors: In-silico Design and Synthesis Yoshio Hamada, Harichandra D. Tagad, Yoshiaki Kiso Design of Novel Relaxin-3 Agonist Analogues as Potential Neurological Regulators Fazel Shabanpoor, M. Akhter Hossain, Feng Lin, Ross A.D. Bathgate, Andrew Gundlach, John D. Wade 2-Oxoamides Based on Amino Acids and Dipeptides as Selective Phospholipase A2 Inhibitors Presenting Anti-inflammatory Activity George Kokotos N-Methylation of Cyclized Melanotropine Peptides: A New Perspective of Drug Discovery for Melanocortin System Minying Cai, Jennifer Bao, Morgan R. Zingsheim, Johannes G.Beck, Florian Opperer, Lucas Doedens, Horst Kessler Victor J. Hruby Design, Synthesis, and Pharmacological Evaluation of Novel Tasiamide B Derivatives: Selective Inhibitors of BACE1 Jian Liu, SimingYang, Wei Zhang, Ning Ding, Yingxia Li Autophagy Inhibition Promotes HDACI-induced Apoptosis in MCF-7 Breast Cancer Cells Shimiao Wang, Xiaohui Li, Zhilong Xiu The Mechanism of Amyloid Protein Aggregation and the Design of Fibrillization Inhibitors Meng-Rong Ma and Yan-Mei Li Anti-HIV-1 Small Molecule-Peptide Conjugates for Studying Target Binding of Small Molecule Fusion Inhibitors Chao Wang, Weiguo Shi, Lifeng Cai, Kun Wang, Keliang Liu A Peptide-based Fluorescence Probe for Trypsin Activity and a Potent Inhibitor Junchen Wu, Tian He, Carsten Schmuck Development of RGD-MEK1/2 Inhibitor Conjugates for Targeted Delivery in Melanoma Treatment Xiaoxiao Li, Cao Wang, Shanyun Gao, Jianjun Hou, Zhangjun Yang, Lihe Zhang, Zili Chen, Yun Wu Chemical Synthesis of Irisin and Detection in Human Blood Aydar Sabirov, Xiang-Qun Chen, Rong-Ming Lyu, Qing Tian, Siok L.Dun Nae J. Dun, and Jaw-Kang Chang Bifunctional Peptides with a μ/δ Opioid Activity Profile as Analgesic Drug Candidates with Reduced Side Effects Jinguo Ding, Thi M.-D. Nguyen, Carole Lemieux, Nga N. Chung, and Peter W. Schiller Discovery and Mechanism of a New Antitumor Peptide Liangyou Wang, Dongdong Lu Session 5 Peptide Mimetics and Conjugates Exploring the Function and Transport Mechanism of Lipidated Proteins Using Synthetic Proteins Si-Yu Zhang, Yong-Xiang Chen Session 6 Bioactive Peptides Cationic Antifungal Lipopeptides: Conjugation of a Fatty Acid Compensates for Shortening the Peptidic Chain Dorit Avrahami and Yechiel Shai Cyclic ω-conotoxin MVIIA, Antimicrobial Activity Generated by Cyclization Xinya Hemu and James P. Tam STY39, a Novel Alpha-Melanocyte-stimulating Hormone Analogue, Reduces Acute Lung Injury in Rats with Hemorrhagic Shock and Endotoxin Challenge Zhigang Wang, Yeping Tian Author Index Subject Index |
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