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书名 林志彬教授从事医学教育科研工作50周年论文选集(1961-2011)
分类 文学艺术-传记-传记
作者 林志彬
出版社 北京大学医学出版社
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《林志彬教授从事医学教育、科研工作50周年论文选集(1961-2011)》收录包括原著论文、综述、述评、讲座和科普文章等。林志彬教授在“把握机遇,执著追求”一文中谈到了参加西医脱产学习中医班后研究思想的转变,即从西医的观点转变为中西医结合的观点,立足于在中医传统理论和临床实践的基础上,采用现代科技方法研究中医的治则如“扶正固本”、“扶正祛邪”、“异病同治”等。在这些研究的基础上,对灵芝的“扶正固本”、“扶正祛邪”治则进行了探讨,选集中的“中医药传统理论指导灵芝的中西医结合研究”、“中西医结合研究诠释灵芝的扶正固本功效”二文即是中西医结合探讨灵芝的扶正固本(扶正祛邪)作用的文章。而选集中“灵芝预防流行性感冒的根据:正气存内,邪不可干”、“科学理解灵芝辅助治疗肿瘤的疗效”、“灵芝抗肿瘤研究的思考——扶正祛邪和与癌共存”等文也反映了作者从中西医结合的角度探讨如何合理应用灵芝防病治病、如何科学地评价其疗效,并对药品的GCP临床试验标准有了新的看法。

目录

专文、述评、综述、专栏、讲坛

 把握机遇执著追求

 回顾20世纪中国药理学的发展历程

 灵芝多糖的免疫药理学研究及其意义

 中医药传统理论指导灵芝的中西医结合研究

 灵芝三萜类化合物药理作用研究进展

 灵芝抗肿瘤活性和免疫调节作用的研究进展

 灵芝孢子及其活性成分的药理研究

 灵芝预防流行性感冒的根据——“正气存内,邪不可干

 科学理解灵芝辅助治疗肿瘤的疗效

 中西医结合研究诠释灵芝的扶正固本功效

 灵芝抗肿瘤研究的思考——扶正祛邪和与癌共存

 Focus on Anti-Oxidative and Free Radical Scavenging Activity of Ganoderma lucidum

 Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms

 Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum

原著论文

 裂褶菌孢内多糖和孢外多糖对小鼠免疫功能的影响

 银耳多糖对小鼠脾细胞产生白细胞介素2(IL2)的影响

 灵芝多糖对老年小鼠脾细胞DNA多聚酶α活性及免疫功能的影响

 香菇多糖的免疫调节作用

 银耳多糖对小鼠IL-2、IL-6、TNFα活性及其mRNA表达的影响

 灵芝菌丝体多糖对HL-60细胞凋亡的影响

 灵芝多糖肽拮抗吗啡的免疫抑制作用的体外试验

 灵芝多糖GL-B的抑瘤作用和机制研究

 用血清药理学方法研究灵芝浸膏GLE的抗肿瘤作用机制

 赤芝子实体新三萜化合物的结构鉴定

 羧甲基茯苓多糖对小鼠免疫功能的影响

 灵芝孢子和破壁孢子多糖对体外培养的小鼠脾淋巴细胞及腹腔巨噬细胞免疫调节活性的比较

 灵芝菌株的DNA指纹分析

 灵芝甾醇对大鼠局灶性脑缺血再灌注损伤的保护作用

 灵芝多糖对甲氨蝶呤诱导的小鼠肠道损伤的保护作用

 灵芝多糖对:IEC-6细胞促增殖、迁移与分化作用

 灵芝益甘粉对D-氨基半乳糖诱导小鼠肝损伤的保护作用研究

 EFFECTS OF GANODERMA POLYSACCHARIDES ON THE ACTIVITY OF DNA

POLYMERASE a IN SPLEEN CELLS STIMULATED BY ALLOANTIGENS IN

MICE IN VITRO

 EFFECTS OF GANODERMA POLYSACCHARIDES ON IL-2 PRODUCTON BY MOUSE

SPLENOCYTES IN VITRO

 Effects of Tremella Polysaccharide on Immune Function of Physically--Stressed Mice

 A NEW LANOSTANE-TYPE TRITERPENE FROM THE FRUITING BODIES OF

GANODERMA LUCIDUM

 Protective effects of Ganoderma lucidum polysaecharides peptide on injury of macrophages

induced by reactive oxygen species

 Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides

 Regulatory effect of Ganoderma lucidum polysaccharides on cytotoxic T-lymphocytes induced

by dendritic cells in vitro

 Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver

injury in mice

 Effects of Total Triterpenoids Extract from Ganoderma lucidum (Curt. : Fr. ) P. Karst.

(Reishi Mushroom) on Experimental Liver Injury Models Induced by Carbon Tetrachloride or

D-Galactosamine in Mice

 In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced

pancreatic islets damage

 Effect of Agaricus brasiliensis S. Wasser et al. (Agaricomycetideae) Extract on the Functions

of Lymphocytes in Mice in Vitro

 Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide

 Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical

Neurons From Hypoxia/Reoxygenation Injury

 Hypoglycemic effect of Ganoderma lucidum polysaccharides

 Ganoderma total sterol (GS) and GS1 protect rat cerebral cortical neurons from hypoxia/

reoxygenation injury

 Effects of Ganoderma lucidum polysaccharides on proliferation and cytotoxicity of cytokine-

induced killer cells

 Modulation of cytokines production, granzyme B and perforin in murine CIK cells by

Ganoderma lucidum polysaccharides

 Effect of Grifola frondosa (Dicks. : Fr. ) S. F. Gray (Maitake Mushroom) Aqueous Extract

on Nitric Oxide Production Induced by BCG and Cytokines in Rat Hepatocytes

 Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and

the induction of VEGF in human lung cancer cell

 Effect of polysaccharides from Ganoderma lucidum on streptozotocin-induced diabetic

nephropathy in mice

 Ganoderma lucidum polysaccharides enhance the function of immunological effector cells in

immunosuppressed mice

 Effects of Ganoderma lucidum Polysaccharide on CYP2E1, CYPIA2 and CYP3A Activities

in BCG-Immune Hepatic Injury in Rats

 Reversal effect of Ganoderma lucidum polysaccharide on multidrug resistance in K562/ADM

cell line

 Effect of Ganoderma lucidum capsules on T lymphocyte subsets in football players on "living

High-training low"

 Promoting Effects of Ganoderma lucidum Polysaccharides on B16F10 Cells to Activate

Lymphocytes

 Ganoderma lucidum polysaccharides antagonize the suppression on lymphocytes induced by

culture supernatants of B16F10 melanoma cells

附录 林志彬教授主要论著目录

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