甄永苏，微生物药学和肿瘤药理学家，医药生物技术专家。长期从事抗肿瘤抗生素研究，是中国早期开展该领域工作的研究者之一。

《甄永苏院士集》是《中国医学院士文库》的分册之一。本书由五部分组成。第一部分奋斗历程，介绍了院士的主要经历和事业发展的宝贵经验；第二部分学术贡献，第三部分治学之道，阐述了院士的创新意识、严谨作风和刻苦精神；第四部分大师风范，第五部分人生风采。全书充分诠释了甄永苏院士的学术成就、学术思想和学术风范。

《甄永苏院士集》是《中国医学院士文库》的分册之一。本书由五部分组成。第一部分奋斗历程，介绍了院士的主要经历和事业发展的宝贵经验；第二部分学术贡献，包括院士的主要学术论文、学术著作以及学术年表等，反映了院士在理论创新和技术进步方面的主要成果及其价值；第三部分治学之道，阐述了院士的创新意识、严谨作风和刻苦精神；第四部分大师风范，记载了院士在培养人才和团队建设上为人师表的生动事例；第五部分人生风采，以丰富的图片资料展示了院士在不同时期工作、讲学、国际交流、社会活动和业余生活等方方面面的风采。全书充分诠释了甄永苏院士的学术成就、学术思想和学术风范，可供广大医学工作者，特别是从事药学、科研、教学的专业人员学习、借鉴。

第一部分 奋斗历程

 我的科研历程

 天然来源的抗肿瘤药物研究与开发的典范

第二部分 学术贡献

 一、甄永苏院士的主要学术论文

五种抗肿瘤药物对小鼠各种组织损害作用的比较

N-甲酰溶肉瘤素对小鼠精原细胞的损害作用

小鼠各种组织细胞对N-甲酰溶肉瘤素敏感性的比较——病理形态和细胞计数的研究

The Murine Spermatogonial Depletion Assay as A Method for Primary Screening of Antitumour Substances

抗肿瘤药物初筛方法——精原细胞法和噬茵体法的比较研究

争光霉素A5和争光霉素A2的抗肿瘤作用与毒性研究

Dexamethasone Synergistically Induces Chemotactic Peptide Receptor Expression in HL-60 Cells

A Human Granulocyte-Specific Antigen Characterized by Use of Monoclonal Antibodies

Effects of Acivicin and Dipyridamole on Hepatoma 3924A Cells

Amphotericin B Renders Stationary Phase Hepatoma Cells Sensitive to Dipyridamole

抗CCT2单克隆抗体和争光霉素A。结合物的抗白血病细胞活性

博来霉素A6抗人体肝癌的实验研究

Amphotericin B：A Biological Response Modifier in Targeting Against the Salvage Pathways

A New Macromolecular Antitumor Antibiotic，C一1027 III．Antitumor Activity

Potentiation of Antimetabolite Antitumor Activity in Vivo by Dipyridamole and Amphotericin B

Mode of Action of C-1027，A New Macromolecular Antitumor Antibiotic

With Highly Potent Cytotoxicity，on Human Hepatoma BEL-7402 Cells

博来霉素A6对小鼠肺毒性的电子显微镜观察

Green Tea Extract Inhibits Nucleoside Transport and Potentiates the Antitumor Effect of Antimetabolites

Azidothymidine and Dipyridamole as Biochemical Response Modifiers Synergism with Methotrexate and

5-Fluorouracil in Human Colon and Pancreatic Carcinoma Cells

Antitumor Activity of Immunoconjugates Composed of Boanmycin and Monoclonal Antibody

Novel Nucleoside Transport Inhibitors of Natural Origin

A Single Binding Mode of Activated Enediyne C1027 Generates Two Types of Double-Strand

DNA Lesions: Deuterium Isotope-Induced Shuttling Between Adjacent Nucleotide Target Sites

Antibiotic C3368-A, A Fungus-Derived Nucleoside Transport Inhibitor, Potentiates the Activity of Antitumor Drugs

Induction of Apoptosis by Enediyne Antitumor Antibiotic C1027 in HL-60 Human Promyelocytic Leukemia Cells

Antitumor Activity of Yunnanmycin A Novel Pyrimidine Nuc|eoside Antibiotic

Antitumor Components From an Actinomycete Strain 6011W

Cinnamamide, an Antitumor Agent With Low Cytotoxicity Acting on Matrix Metalloproteinase

Intracellular Expression of A Single-Chain Antibody Directed Against

Type Ⅳ Collagenase Inhibits the Growth of Lung Cancer Xenografts in Nude Mice

Activity of Boanmycin Against Colorectal Cancer

大黄素抑制人高转移巨细胞肺癌PG细胞的肿瘤转移相关性质

Antitumor Effects of Monoclonal Antibody Fab Fragment-Containing Immunoconjugates

Antitumor Effects of the Molecule-Downsized Immunoconjugate Composed of Lidamycin

and Fab Fragment of Monoclonal Antibody Directed Against Type Ⅳ Collagenase

HERG K+ Channel Expression-Related Chemosensitivity in Cancer Cells and Its Modulation by Erythromycin

An Enediyne-Energized Single-Domain Antibody-Containing Fusion Protein Shows Potent Antitumor Activity

Down-Regulation of the Nuclear Factor-kB by Lidamyein in Association With Inducing

Apoptosis in Human Pancreatic Cancer Cells and Inhibiting Xenograft Growth

Synergy of Gemcitabine and Lidamycin Associated With NF-kB Downregulation in Pancreatic Carcinoma Cells

Binding Capability of the Enediyne-Associated Apoprotein to Human Tumors and

Constitution of A Ligand Oligopeptide-Integrated Protein

Enediyne Lidamycin Enhances the Effect of Epidermal Growth Factor Receptor Tyrosine

Kinase Inhibitor, Gefitinib, in Epidermoid Carcinoma A431 Cells and Lung Carcinoma H460 Cells

Lidamycin Shows Highly Potent Cytotoxic to Myeloma Cells and Inhibits Tumor Growth in Mice

Rhein Lysinate Suppresses the Growth of Breast Cancer Cells and Potentiates the

Inhibitory Effect of Taxol in Athymic Mice

A Bispecific Enediyne-Energized Fusion Protein Containing Ligand-Based and Antibody-

Based Oligopeptides Against Epidermal Growth Factor Receptor and Human Epidermal

Growth Factor Receptor 2 Shows Potent Antitumor Activity

A Tandem ScFv-Based Fusion Protein and Its Enediyne-Energized Analogue Show

Intensified Therapeutic Efficacy Against Lung Carcinoma Xenograft in AthymicMice

Endostar, A Modified Recombinant Human Endostatin, Exhibits Synergistic Effects

With Dexamethasone on Angiogenesis and Hepatoma Growth

Antitumor Efficacy of the scFv-Based Fusion Protein and Its Enediyne-Energized

Analogue Directed Against Epidermal Growth Factor Receptor

Pingyangmycin Downregulates the Expression of EGFR and Enhances the Effects of

Cetuximab on Esophageal Cancer Cells and the Xenograft in Athymic Mice

An NGR-Integrated and Enediyne-Energized Apoprotein Shows CD13-Targeting

Antitumor Activity

Lidamycin Inhibits Tumor Growth and Pulmonary Metastasis in Murine Breast

Carcinoma and Shows Synergy With Paclitaxel

抗肿瘤导向药物研究的现状与展望

天然来源的新型抗肿瘤生化调节剂

抗肿瘤抗生素和治疗肿瘤的单克隆抗体药物

抗体药物靶向治疗肿瘤前景广阔

抗肿瘤抗生素平阳霉素研究与临床应用40年

 二、甄永苏院士的主要学术著作

TEA

抗体工程药物

抗体药物研究与应用

抗肿瘤药物研究与开发

 三、甄永苏院士学术年表

个人简历

甄永苏院士论文目录

甄永苏院士参加的主要学术会议与报告

甄永苏院士著作目录

甄永苏院士培养研究生名录

甄永苏院士已获授权的专利项目

第三部分 治学之道

 科技创新的认识与实践

 勤奋敬业 乐群

 沙里淘金费苦辛 药中奥妙细追寻——记中国工程院院士甄永苏教授

 甄永苏：科研贵在创新

第四部分 大师风范

 甄永苏院士——我们的良师益友

 写在甄永苏院士从业60周年前夕

 在甄永苏老师身边学习和工作的日子

 在甄老师身边多年的一些感悟

 回忆甄老师指导我如何作好科研报告

 我认识的甄老师

 在院士身边做博士

 尊敬的师长，真正的大师

 与甄永苏院士的师生缘

 桃李芬芳引路人青丝华发闪师恩

 上善若水，大爱无痕

第五部分 人生风采

 美满家庭

 校友情深

 学科建设

 学术活动

 国际交流

 重要时刻

 院士活动