The clinical laboratory has long functioned as a dynamic environment in which new technologies constantly challenge us by their implementation in new diagnostic tests.With the clinical laboratory is now challenged by yet another technological advancement,sis of nucleic acids……
Preface
List of Contributors
Part I Basic Molecular Biology
1 A Historical Perspective on the Clinical Diagnostic Laboratory
2 An Overview of Nucleic Acid Chemistry,Structure,and Function:The Foundations of Molecular Biology
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Part II Molecular Technologies
4 Nucleic Acid Blotting Techniques:Theory and Practice
5 DNA Amplification Techniques:An Overview
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Part III Applications To Molecular Pathology
10 An Overview of Molecular Genetics
11 Genetic Basis of Neurologic and Neuromuscular Diseases
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Part IV Issues For The Clinical Molecular Pathology Laboratory
17 Quality Control Issues for the Clinical Molecular Pathologist
18 Prospects for the Future Role of the Clinical Laboratory
Genetic disorders account for a significant amount of human disease.About 4% of all infants born in the United States and Canada are affected by a birth defect.Approximately 1 in 200 births is affected by a chromosomal abnormality.