The 11th Chinese International Peptide Symposium (CPS-2010), hosted by Lanzhou University, was held in Lanzhou, China, July 5-8, 2010. More than 300 participants, from 12 countries and districts as well as represents from 30 or so related companies attended this symposium. Thus, it was gratifying to see that this meeting retained both its international flavor and participants loyalty at a time when there are a great many symposia held each year on similar subjects. The goal of this symposium was to provide a forum for exchange of ideas, review of the progress in the field of peptide research, encourage the cooperation between the international and Chinese scientific communities. We believe that this goal had been achieved.

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Preface

The Eleventh Chinese Peptide Symposium (CPS-2010)

Acknowledgments

Cathay Award

Xiaoyu Hu Memorial Award

Chinese Peptide Symposium

Abbreviations

Session 1 Design of Peptides and Mimetics

Biomimetic Nanostructures Based on Enforced Folding and Assembly

Agonist vs. Antagonist Behavior of Opioid Peptides Containing Novel Tyrosine or Phenylalanine Analogues in Place of Tyr1

Novel Non-Peptide Ghrelin Receptor Ligands Based on 3,4,5-Trisubstituted 1,2,4-Triazoles

Synthesis and Structure-Activity Relationship of Marinostatin,An Ester-Linked Serine Protease Inhibitor

Mitocryptides: A Novel Family of Neutrophil-Activating Peptides Derived from Mitochondrial Proteins and Their Regulatory Mechanisms

Novel Opioid Peptide Derived Antagonists Containing 3-(2,6- Dimethyl-4-Carbamoylphenyl)-Propanoic Acid (Dcp) in Place of Tyr1

Session 2 Peptide Synthesis and Preparation

Synthetic Studies of Membrane Proteins: Subunit C of Human F1Fo-ATP Synthase and Voltage Sensor Only Protein (78-222)

One-Pot Synthesis of Rigid Cyclic N-Methyl-γ-Peptides

Tbfmoc Methioine: Its Synthesis and Application for the Solid Phase Synthesis of Ubiquitin Analogues and Product Purification

Intein-Mediated Biosynthesis of Bracelet Cyclotide

Convergent and Atom-Economic Synthesis of Phosphinopeptides

One-Step Oxidative Folding of A Novel Cystine-Knot Cyclotide Under Denaturation Conditions

Synthesis of Angiotensin I-Converting Enzyme Inhibitory Peptides and Their Self-Assembling Microstructure Characterization

Fast Automated Synthesis of An Antimicrobial Peptide Analog Using UV-Monitoring on the Tribute？

Synthesis of Cyclic Peptides by Alknye-Azide Click Chemistry Cyclization

Thioester Preparation through O-S Acyl Shift under Acidic Condition

A Novel Strategy for Total Solid-Phase Synthesis of Kahalalide A Derivatives

Thioester Preparation through O-S Acyl Shift under Acidic Condition

A Novel Strategy for Total Solid-Phase Synthesis of Kahalalide A Derivatives

Session 3 Methodologies in Peptide Research

Protein Synthesis Using Novel Ligation Partners

Expanding Role of Mass Spectrometry for Characterization of Proteins

Effect of pH on the Self-Assembly of Surfactant-Like Peptides

Conformational Isomers in N-Methylzygosporamide Cyclic Pentapeptides

Interaction between Amyloid-β-Peptide (1-40) and Its Aggregation Inhibitors Studied by Circular Dichroism

Disulfide Bond Formation Directed by Watson-Crick Base Pairing

Interfacial Adsorption of Novel Lipopeptide Surfactant C14K3: A Combined Study of Spectroscopic Ellipsometry and Neutron Reflection

Session 4 Peptide Therapeutics and Appfication

Peptide-Based Nanoparticles for Cancer Therapy and Imaging

Involvement of Na ,K -ATPase in Leukemia Cell Apoptosis by Modulating Sensitivity

Short Constrained Dipeptide Mimic Oligomers as Uncharged Cell Penetrating Compounds

Synthesis and Biological Properties of Peptide-siRNA Conjugates

FGF-P Facilitates Cell Proliferation Following Ionizing Radiation

Synthesis, Evaluation and Molecular Modeling Study of L-2-amino-7/8-Bromoalkanoic Acid Derivatives as Histone Deacetylase Inhibitors

Thirteen-Membered Cyclic Tetrapeptides as Histone Deacetylase Inhibitors

Antimicrobial Peptide May be Desirable Candidate for the Treatment of

 Multidrug-Resistant Cancer & Bacteria: A Simple Introduction to the

 Therapeutic Effects of A Novel Antimicrobial Peptide Polybia-MPI

Remodeling of Cyclic Tetrapeptides Framework of Chlamydocin as Historic Deacetylase Inhibitors

Identification of Novel HLA-A*0201-Restricted Cytotoxic T lymphocyte Epitopes from PLAC 1 in Breast Cancer

Session 5 Bioactive Peptides and Pharmacology

In Vitro Characterization for the Effects of Insect Kinins on Mouse Distal Colonic Motility

Evaluation of the Bioequivalence of the 20 mg/10 ml Doses of Two

 Injectable Preparations of Eptifibatide: A Randomized, Open-Label,

 Two-Period Crossover Study in Healthy Adult Male Chinese Volunteers

The Characteristics of Sleep-Wake States and Potential Neuronal Targets for Neuropeptide S

Antibacterial Activity of Surfactant-Like Linear Amphipathic Cationic Peptides

Comparison of the Pharmacological Functions of the NPFF1 and NPFF2 Receptors Ligands

Preparation of Monomeric B27 Lys Destripeptide Insulin by Intein Mediated Expression in E. Coli

Endomorphins Prevent Cardiac Oxidative Damage Induced by Cadmium Chloride in Rats

Study on Anticancer Mechanism of Cyclic Tetrapeptide HDACIs

Biological Roles ofHemokinin-l: A Novel Member of the Tachykinin Family

Author Index

Subject Index