《生命科学新视野》丛书精选Trends、Current Opinion和Drug Discovery Today等系列出版物中的部分最新论文，以原文稍加中文注解的形式，按专题编辑成册。本书为其中一册，共有25篇文章，涉及系统生物学、微生物与人类疾病、噬菌体多样性、基因转移与进化、生物修复与生物强化、III型分泌系统等内容。

本书将主要面向大学高年级学生、教师、研究生以及科研工作者，供其参考和收藏。

中文摘要

系统生物学

Building functional modules from molecular interactions

Klaus Peter Hofmann，Christian M.T.Spahn,Reinhart，Heinrich and Udo Heinemann

通过分子互作逐渐构建功能性模块

Systems analyses characterize integrated functions of biochemical networks

Erwin P.Gianchandani，David L.Brautigan and Jason A.Papin

应用系统分析对生化网络整合功能的特征分析

微生物与人类疾病

Beyond diversity：functional microbiomics of the human colon

Markus Egert，Albert A.de Graaf，Hauke Smidt,Willem M.de Vos and Koen Venema

人类结肠的功能微生物组学：不只是个多样性问题

New trends in antigen uptake in the gut mucosa

Florence Niedergang and Mi-Na Kweon

胃肠粘膜抗原摄取的新认识

Bacterial contributions to mammalian gut development

Lora V.Hooper

哺乳动物胃肠道发育过程中细菌的贡献

Gastric autoimmunity：the role of Helicobacter pylori and molecular mimicry

Mano M.D'Elios.Ben J.Appelmelk，Amedeo Amedei,Mathijs P.Bergman and Gianfranco Del Prete

胃的自身免疫：幽门螺杆菌的作用与分子模拟

How do DCs interact with intestinal antigens?

Simon W.F.Milling，Lesley Cousins and G.Gordon MacPherson

树突状细胞是怎样与肠道抗原相互作用的?

NLRs join TLRs as innate sensors of pathogens

Fabio Martinon and Jurg Tschopp

NLRs加盟TLRs成为病原的先天感应器

Sugar-mediated ligand-receptor interactions in the immune system

Pauline M.Rudd，Mark R.Wormald and Raymond A.Dwek

免疫系统中由糖介导的配体一受体相互作用

Friend or foe?Antimicrobial peptides trigger pathogen virulence

Jennifer L.Bishop and B.Brett Finlay

朋友还是敌人?抗菌肽可以诱发病原的毒力

噬菌体多样性、基因转移与进化

Agrobacterium is not alone：gene transfer to plants by viruses and other bacteria

Sang-Min Chung，Manusha Vaidya and Tzvi Tzfira

农杆菌并不孤独：用于植物基因转移的病毒和其它细菌

Pathogenicity islands and phages in Vibrio cholerae evolution

Shah M.Famque and John J.Mekalanos

霍乱弧菌进化中的毒力岛和噬菌体

Bacteriophages and biotechnology：vaccines，gene therapy and antibacterials

Jason R.Clark and John B.March

细菌噬菌体与生物技术：疫苗、基因治疗和抗菌物质

Survival strategies of infectious biofilms

C.A.Fux.J,W.Costerton，P.S.Stewart and P.Stoodley

传染性生物膜的存活策略

Population genomics in natural microbial communities

Rachel J.Whitaker and Jillian F.Banfield

自然界中微生物的群体基因组学

Genome diversity in microbial eukaryotes

Casey L.McGrath and Laum A Katz

真核微生物基因组的多样性

生物修复/生物强化

Biofilms：implications in bioremediation

Rajbir Singh，Debarati Paul and Rakesh K.Jain

生物膜：对生物修复的启示

Microbial degradation of sulfur，nitrogen and oxygen heterocYcIes

Pina Xu,Bo Yu，Fu Li Li，Xiao Feng Cai and Cui Qing Ma

硫氮氧杂环化合物的微生物降解

Towards commercial production of microbial surfactants

Soumen Mukhedee，Palashpriya Das and Ramkrishna Sen

微生物表面活性剂的商业化生产趋势

EnvironmentaI biocatalysis：from remediation with enzymes to noVel green Processes

Miguel AIcaide.Manuel Feffer，Francisco J.Plou and Antonio BallesterOs

环境生物催化：从酶介生物修复到新型绿色加工

Bioremediation of weathered-building stone surfaces

Alison Webster and Eric May

建筑物石头风化表面的生物修复

Laccases：blue enzymes for green chemistry

Sergio Riva

漆酶：用于绿色化学的蓝色酶

|||型分泌系统

Mickael Desva uxl Michel Hebraud，lan R.Henderson and Mark J.Pallen

细菌|||型分泌系统：到底讲的是什么?

New structural insights into the bacterial type||| secretion system

Calvin K.Yip and Natalie C.J.Strynadka

细菌|||型分泌系统结构的新认识

The functional interface between Salmonella and its host cell：opportunities for theraPeutic intervention

Javesh C.Patel.Olivia W.Rossanese and Jorge E.Galan

沙门氏菌与宿主细胞互作的功能性界面：治疗性干预的机会