近二十年来，抗新生血管药物及抗炎药物眼内缓释剂的出现，更加速了药物在眼内的临床应用，取得了可喜的治疗效果。目前，许多累及眼内结构的疾病，都得以通过眼内用药进行治疗，既能使药物直接作用于靶组织，又减轻甚至避免了药物全身应用的并发症，但是，眼内药物的种类越来越多，所治疗的眼病也愈加复杂，如何更合理、规范地眼内用药，仍是眼科医生面临的问题。该书全面、系统地介绍眼内用药的相关理论与临床实际应用经验，可为眼科医生的临床眼内用药提供参考与帮助。

第一篇　眼内用药总论第一章　眼对药物的屏障作用与眼内用药 ..........................................3第一节　眼对药物的屏障作用 ...................................................................................3第二节　眼内用药的药代动力学 ...............................................................................4第二章　 眼内用药的发展过程 .........................................................7第一节　眼内用药的过去 ...........................................................................................7第二节　眼内用药的现状 ...........................................................................................7第三节　眼内用药的未来 ...........................................................................................8第三章　常用于眼内的药物 ...........................................................15第一节　抗新生血管药物 .........................................................................................15第二节　抗细菌药物 .................................................................................................21第三节　抗真菌药物 .................................................................................................24第四节　抗病毒药物 .................................................................................................28第五节　皮质类固醇激素 .........................................................................................29第四章　眼内用药途径及应考虑的问题 ...........................................39第一节　眼内用药途径 .............................................................................................39第二节　眼内用药应考虑的问题 .............................................................................40第五章　玻璃体腔药物注射方法 .....................................................49第一节　患者准备 .....................................................................................................49第二节　注射操作 .....................................................................................................51第三节　眼内注射后的检查与复诊 .........................................................................53第四节　玻璃体腔注射的并发症 .............................................................................54第六章　眼内注射的并发症 ...........................................................55第一节　感染性眼内炎及药物相关眼内炎症 .........................................................55第二节　眼内压升高与眼部出血 .............................................................................56第三节　裂孔源性视网膜脱离与玻璃体视网膜纤维增殖 .....................................57第四节　罕见的眼部和全身性不良反应 .................................................................58第五节　抗VEGF药物注射后特定疾病的不良事件 .............................................58第二篇　眼内用药各论第七章　真菌性角膜炎的眼内用药 ..................................................67第一节　概述 .............................................................................................................67第二节　治疗原则 .....................................................................................................68第三节　眼内用药治疗 .............................................................................................69第四节　后续治疗与疗效评估 .................................................................................73第八章　与白内障手术相关的眼内用药 ...........................................76第一节　概述 .............................................................................................................76第二节　白内障手术相关前房注药的类型 .............................................................77第三节　白内障手术前房注药的注意事项 .............................................................78第四节　白内障手术前房注药的发展趋势 .............................................................79第九章　新生血管性年龄相关性黄斑变性的眼内用药 .........................82第一节　概述 .............................................................................................................82第二节　nAMD的临床特征与检查 .........................................................................82第三节　nAMD的发病机制 .....................................................................................84第四节　nAMD的治疗原则与眼内用药时机 .........................................................85第五节　眼内用药的后续治疗 .................................................................................92第十章　息肉样脉络膜血管病变的眼内用药 .....................................96第一节　概述 .............................................................................................................96第二节　治疗原则与时机 .........................................................................................97第三节　眼内用药方案 .............................................................................................97第四节　眼内用药的后续治疗 .................................................................................99第十一章　糖尿病视网膜病变的眼内用药 ......................................104第一节　概述 ...........................................................................................................104第二节　DR的药物治疗 .........................................................................................105第三节　DR的治疗时机与方案 .............................................................................106第四节　眼内用药的后续治疗 ................................................................................115第十二章　早产儿视网膜病变的眼内用药 ......................................122第一节　概述 ...........................................................................................................122第二节　治疗原则 ...................................................................................................124第三节　眼内用药治疗方案 ...................................................................................125第四节　眼内用药的疗效和后续治疗 ...................................................................127第十三章　新生血管性青光眼的眼内用药 ......................................129第一节　概述 ...........................................................................................................129第二节　治疗原则 ...................................................................................................130第三节　眼内用药方案 ...........................................................................................131第四节　眼内用药的后续治疗 ...............................................................................132第十四章　特发性CNV的眼内用药 .............................................136第一节　概述 ...........................................................................................................136第二节　治疗原则 ...................................................................................................137第三节　眼内用药的时机和方案 ...........................................................................137第十五章　近视性CNV的眼内用药 .............................................141第一节　概述 ...........................................................................................................141第二节　治疗原则 ...................................................................................................143第三节　眼内用药的时机和方案 ...........................................................................144第四节　眼内用药效果评估和后续治疗 ...............................................................144第十六章　其他CNV的眼内用药 .................................................150第一节　由炎症导致的CNV ..................................................................................150第二节　由慢性中心性浆液性脉络膜视网膜病变继发的CNV ..........................152第三节　由血管样条纹和脉络膜塌陷继发的CNV ..............................................154第十七章　视网膜静脉阻塞黄斑水肿的眼内用药 .............................159第一节　概述 ...........................................................................................................159第二节　治疗原则 ...................................................................................................160第三节　眼内用药方案 ...........................................................................................161第四节　眼内用药的后续治疗 ...............................................................................161第十八章　外层渗出性视网膜病变的眼内用药 ................................164第一节　概述 ...........................................................................................................164第二节　治疗原则 ...................................................................................................165第三节　眼内用药方案 ...........................................................................................165第四节　眼内用药的后续治疗 ...............................................................................166第十九章　急性视网膜坏死的眼内用药 .........................................168第一节　概述 ...........................................................................................................168第二节　眼内用药原则 ...........................................................................................169第三节　眼内用药方案 ...........................................................................................169第四节　眼内用药的后续治疗 ...............................................................................170第二十章　非感染性葡萄膜炎的眼内用药 ......................................172第一节　概述 ...........................................................................................................172第二节　眼内用药原则 ...........................................................................................173第三节　眼内用药方案 ...........................................................................................174第四节　眼内用药的后续治疗 ...............................................................................175第二十一章　视网膜静脉周围炎的眼内用药 ...................................178第一节　概述 ...........................................................................................................178第二节　疾病的发生机制 .......................................................................................179第三节　治疗原则与用药时机 ...............................................................................180第四节　眼内用药的后续治疗 ...............................................................................181第二十二章　感染性眼内炎的眼内用药 .........................................185第一节　概述 ...........................................................................................................185第二节　临床特征 ...................................................................................................186第三节　诊断要点与实验室检查 ...........................................................................187第四节　病原菌谱与治疗原则 ...............................................................................190第五节　玻璃体腔药物注射治疗 ...........................................................................192第六节　疗效评估与后续治疗 ...............................................................................196第二十三章　视网膜母细胞瘤的眼内用药 ......................................198第一节　概述 ...........................................................................................................198第二节　视网膜母细胞瘤的治疗 ...........................................................................199第三节　视网膜母细胞瘤的种植与玻璃体腔用药 ...............................................201第四节　玻璃体腔用药与其他治疗的联合 ...........................................................203第五节　眼内化疗药物的准备与注射方法 ...........................................................203第六节　视网膜母细胞瘤眼内用药的毒性与注意事项 .......................................204附录一　英文缩写词 ..................................................................209附录二　关于超说明书用药 .........................................................213